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2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL) PYRIDINE-4-BORONIC ACID PINACOL ESTER is a chemical compound that belongs to the pyridine family and contains a boronic acid pinacol ester functional group. It is known for its stability and compatibility with a wide range of reaction conditions, making it a versatile and valuable tool in synthetic chemistry.

880495-84-1

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  • 2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL) PYRIDINE-4-BORONIC ACID PINACOL ESTER

    Cas No: 880495-84-1

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880495-84-1 Usage

Uses

Used in Organic Synthesis:
2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL) PYRIDINE-4-BORONIC ACID PINACOL ESTER is used as a reagent in organic synthesis for facilitating the formation of carbon-carbon and carbon-heteroatom bonds.
Used in Pharmaceutical Industry:
2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL) PYRIDINE-4-BORONIC ACID PINACOL ESTER is used as a building block for the preparation of various pharmaceutical intermediates, contributing to the development of new drugs and therapies.
Used in Agrochemical Industry:
2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL) PYRIDINE-4-BORONIC ACID PINACOL ESTER is used as a building block for the preparation of various agrochemicals, aiding in the development of new pesticides and other agricultural chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 880495-84-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,0,4,9 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 880495-84:
(8*8)+(7*8)+(6*0)+(5*4)+(4*9)+(3*5)+(2*8)+(1*4)=211
211 % 10 = 1
So 880495-84-1 is a valid CAS Registry Number.

880495-84-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl-dimethyl-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]methoxy]silane

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:880495-84-1 SDS

880495-84-1Downstream Products

880495-84-1Relevant articles and documents

PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

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Page/Page column 179, (2021/12/08)

The present invention relates to pyrazolopyrimidine derivatives having dual pharmacological activity towards both the α2δ subunit of the voltage-gated calcium channel and the sigma-1 (σ1) receptor, to processes of preparation of such compounds,

Meta-Selective C-H Borylation of Benzamides and Pyridines by an Iridium-Lewis Acid Bifunctional Catalyst

Yang, Lichen,Uemura, Nao,Nakao, Yoshiaki

supporting information, p. 7972 - 7979 (2019/05/22)

We report herein the iridium-catalyzed meta-selective C-H borylation of benzamides by using a newly designed 2,2′-bipyridine (bpy) ligand bearing an alkylaluminum biphenoxide moiety. We also demonstrate the iridium-catalyzed C3-selective C-H borylation of pyridine with a 1,10-phenanthroline (Phen) ligand bearing an alkylborane moiety. It is proposed that the Lewis acid-base interaction between the Lewis acid moiety and the aminocarbonyl group or the sp2-hybridized nitrogen atom accelerates the reaction and controls the site-selectivity.

Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus

Wiles, Jason A.,Song, Yongsheng,Wang, Qiuping,Lucien, Edlaine,Hashimoto, Akihiro,Cheng, Jijun,Marlor, Christopher W.,Ou, Yangsi,Podos, Steven D.,Thanassi, Jane A.,Thoma, Christy L.,Deshpande, Milind,Pucci, Michael J.,Bradbury, Barton J.

, p. 1277 - 1281 (2007/10/03)

We synthesized a diverse series of 9H-isothiazolo[5,4-b]quinoline-3,4- diones containing heteroaromatic groups at the 7-position via palladium-catalyzed cross-coupling. Many of these compounds demonstrated potent antistaphylococcal activity (MICs ≤2 μg/mL) against a multi-drug-resistant strain (ATCC 700699) and low cytotoxic activity (CC50 > 100 μM) against the human cell line Hep2 (laryngeal carcinoma).

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