131747-45-0 Usage
Description
4-Bromo-2-pyridinemethanol is an organic compound with the molecular formula C6H6BrNO. It is a derivative of pyridine, a heterocyclic compound with a nitrogen atom in the ring structure. The presence of a bromine atom at the 4-position and a hydroxymethyl group at the 2-position gives this compound unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
4-Bromo-2-pyridinemethanol is used as a reagent for the synthesis of bisphosphonate derivatives. These derivatives are compounds that inhibit farnesyl pyrophosphate synthase, an important enzyme in isoprenoid biosynthesis. Inhibition of this enzyme can have therapeutic applications, particularly in the treatment of diseases related to abnormal isoprenoid production.
Additionally, 4-Bromo-2-pyridinemethanol can be utilized in the development of new drugs targeting various medical conditions, given its unique chemical structure and reactivity. Its potential applications in drug discovery and development make it a valuable compound in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 131747-45-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,4 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 131747-45:
(8*1)+(7*3)+(6*1)+(5*7)+(4*4)+(3*7)+(2*4)+(1*5)=120
120 % 10 = 0
So 131747-45-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6BrNO/c7-5-1-2-8-6(3-5)4-9/h1-3,9H,4H2
131747-45-0Relevant articles and documents
Aminopyridyloxypyrazole derivative and preparation method and application thereof
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Paragraph 0075; 0170-0176, (2021/05/19)
The invention relates to an aminopyridyloxypyrazole derivative and a preparation method and application thereof. The structure of the aminopyridyloxypyrazole derivative is shown as a formula (I). The invention provides a brand-new aminopyridyloxypyrazole derivative which has obvious effects of inhibiting TGF [beta] R1 (ALK5) kinase activity and treating cancer or fibrosis related diseases, and the preparation method of the derivative is simple and easy to operate.
INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF
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, (2019/09/30)
The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.
ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF
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Paragraph 0201; 0202; 0203, (2017/04/18)
An ALK kinase inhibitor compound as represented by Formula I, pharmaceutical composition containing the compound, and preparation method and use thereof in the preparation of drugs serving as an ALK inhibitor for treating cancer.