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5-chloro-thiophene-2-carbonimidic acid methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

89379-82-8

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89379-82-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 89379-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,3,7 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89379-82:
(7*8)+(6*9)+(5*3)+(4*7)+(3*9)+(2*8)+(1*2)=198
198 % 10 = 8
So 89379-82-8 is a valid CAS Registry Number.

89379-82-8Downstream Products

89379-82-8Relevant articles and documents

Discovery of selective PDE4B inhibitors

Naganuma, Kenji,Omura, Akifumi,Maekawara, Naomi,Saitoh, Masahiro,Ohkawa, Naoto,Kubota, Takashi,Nagumo, Hiromitsu,Kodama, Toshiyuki,Takemura, Masayoshi,Ohtsuka, Yuji,Nakamura, Junji,Tsujita, Ryuichi,Kawasaki, Koh,Yokoi, Hirotsugu,Kawanishi, Masashi

scheme or table, p. 3174 - 3176 (2010/03/24)

In this study the first PDE4B selective inhibitor is described. Optimization of lead 2-arylpyrimidine derivatives afforded a series of potent PDE4B inhibitors with >100-fold selectivity over the PDE4D isozyme. With a good pharmacokinetic profile, a selected compound exhibited potent anti-inflammatory effects in vivo and showed less emesis compared with Cilomilast.

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