906434-29-5Relevant articles and documents
Quantitative analysis of structure-activity relationship in the acridine serie part 1: Antiparasitic 9-thioaryl-acridine derivatives
Mrozek,Karolak-Wojciechowska,Bsiri,Barbe
, p. 345 - 351 (2007/10/03)
Synthesis and antiparasitic activity vs T. cruzi and L. donovani of a series of 9-thioaryl acridines are reported. A convenient correlation between molecular structure and biological activity is proposed. Results not only agree with the classical interactions of acridines with DNA but also suggest possible role of charge transfer complexes.