99497-93-5Relevant articles and documents
Development of a scalable synthesis of P7C3-A20, a potent neuroprotective agent
Naidoo, Jacinth,Bemben, Christopher J.,Allwein, Shawn R.,Liang, Jue,Pieper, Andrew A.,Ready, Joseph M.
supporting information, p. 4429 - 4431 (2013/07/26)
A scalable synthesis of the neuroprotective agent P7C3-A20 is described. The synthesis has provided hundred-gram batches of the final compound for biological evaluation in rodents primates. The synthesis can be performed without chromatographic purificati
The protective effects of oxyresveratrol imine derivative against hydrogen peroxide-induced cell death in PC12 cells
Hur,Kim,Lee,Lee,Choi
, p. 212 - 218 (2013/04/23)
Oxyresveratrol (2',3,4',5-tetrahydroxystilbene) is a naturally occurring ingredient found in mulberries that shows potential as an antioxidant, anti-inflammatory, and neuroprotective agent. This study was performed to identify materials similar to oxyresv
Nano-tube TiO2 as a new catalyst for eco-friendly synthesis of imines in sunlight
Hosseini-Sarvari, Mona
experimental part, p. 547 - 550 (2012/01/06)
Nanomaterials are considered as suitable heterogeneous catalysts for many organic reactions. Herein nano-tube TiO2 has been reported as a heterogeneous catalyst, for synthesis of imines in sunlight at room temperature under solvent-free conditions. The condensation of less electrophilic carbonyl compounds with poorly nucleophilic amines was afforded imines in excellent yields.
N-Trialkylsilylimines as Coupling Partners for Pd-Catalyzed C-N Bond-Forming Reactions: One-Step Synthesis of Imines and Azadienes from Aryl and Alkenyl Bromides
Barluenga, Jose,Aznar, Fernando,Valdes, Carlos
, p. 343 - 345 (2007/10/03)
A good substitute: Imines, 1-azadienes, 2-azadienes, and even 2-azatrienes are prepared in one step from aryl and alkenyl bromides by palladium-catalyzed cross-coupling with N-trimethylsilylimines. The reaction introduces N-trimethylsilylimines as a synthetic equivalent for the R-CH=N moiety in C-N bond-forming reactions.
