Synthesis and biological evaluation of aminothiazoles against Histoplasma capsulatum and Cryptococcus neoformans

DOI: 10.1016/j.bmc.2018.01.024

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2251 - 2261 (2018)

Update date:2022-08-02

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Authors:

Ishita, Keisuke

Stefanopoulos, Stavros

Khalil, Ahmed

Cheng, Xiaolin

Tjarks, Werner

Rappleye, Chad A.

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Article abstract of DOI:10.1016/j.bmc.2018.01.024

The design and synthesis of a library of forty novel 2-aminoazole analogues as well as their evaluation as antifungal compounds against Histoplasma capsulatum and Cryptococcus neoformans is described. These structures were derived from N-[5-(1-naphthaleny

Full text of DOI:10.1016/j.bmc.2018.01.024

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