Journal of Organic Chemistry p. 782 - 787 (1987)
Update date:2022-08-05
Topics:
Hagen, James P.
Harris, Joseph J.
Lakin, Danielle
Alcoholic, phenolic, and thiolic nucleophiles attack 3-chloro-1-methoxypropene (1) exclusively at C-1 in the presence of N,N-diisopropylethylamine.The reaction is formally a high regioselective SN2' process.Some of the oxygen nucleophiles (e.g.
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