Total synthesis of (±)-heptelidic acid

DOI: 10.1021/ja00232a027

Source and publish data:

Journal of the American Chemical Society p. 8129 - 8133 (1988)

Update date:2022-07-29

Topics:

Authors:

Danishefsky

Mantlo Mantlo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00232a027

The total synthesis of the title compound in 13 steps from 4-isopropylcyclohexanone has been accomplished. The key phases were the following: (i) the use of a cuprate derivative of a diprotected bis allylic alcohol for conjugate addition; (ii) the use of

Full text of DOI:10.1021/ja00232a027

Products guided by the article

Product name:(3R,4RS)-2-(methoxycarbonyl)-4-(1-methylethyl)-1-<(trimethylsilyl)methyl>-3-<3-acetoxy-2-(acetoxymethyl)prop-1-en-1-yl>cyclohex-1-ene

Cas No:116700-83-5

R&D Labs maybe for 116700-83-5

Xinchang Yueding Chemical Co., Ltd.

Contact:86-571-56926323

Address:NO.90 BEIMENCHENGWAI CHENGGUAN TOWN XINCHANG
AstaTech ( Chengdu) BioPharmaceutical Corp.

website:http://www.astabiochem.cn/

Contact:+86-15198215156-15198215156

Address:SICHUAN CHENGDU
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:No.199, Ningbo Avenue, Fengxin industrial park, Fengxin county, Yichun city, Jiangxi
Laohekou Jinghong Chemical Co.,Ltd

Contact:+86-0710-3702747

Address:163.East，Huagong Road，Laohekou
Chemvon Biotechnology Co. Ltd.

website:http://www.chemvon.com

Contact:86-21-58550039;86-21-31268550-8004

Address:Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China

Relevant to this article

CHIRAL COMPLEXING AGENTS AND PHASE-TRANSFER AGENTS. COMMUNICATION 2. SYNTHESIS OF DISUBSTITUTED 18-CROWN-6 ETHERS WITH C₂ SYMMETRY STARTING FROM D-SORBITOL

Doi:10.1007/BF00962666
(1988)
Asymmetric 1,4-dihydroxylation of 1,3-dienes by catalytic enantioselective diboration

Doi:10.1021/ja809610h
(2009)
3,4-dihydro-3//-pyrrol-2-imines as conformationally restrained 1,3-diazabutadienes: Synthesis, structural properties and profanation

Doi:10.1002/ejoc.200900045
(2009)
Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors

Doi:10.1021/jm9004253
(2009)
Enantioselective (3+2) cycloaddition: Via N-heterocyclic carbene-catalyzed addition of homoenolates to cyclic N -sulfonyl trifluoromethylated ketimines: Synthesis of fused N-heterocycle γ-lactams

Doi:10.1039/c9cc09269b
(2020)
Cycloadditions of chiral carbonyl ylides with imine dipolarophiles as a route to enantiomerically pure α-amino-β-hydroxy acids

Doi:10.1016/j.tetasy.2009.02.029
(2009)

Article Doi