
Journal of the American Chemical Society p. 8129 - 8133 (1988)
Update date:2022-07-29
Topics:
Danishefsky
Mantlo
The total synthesis of the title compound in 13 steps from 4-isopropylcyclohexanone has been accomplished. The key phases were the following: (i) the use of a cuprate derivative of a diprotected bis allylic alcohol for conjugate addition; (ii) the use of
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