Synthesis and biological evaluation of a series of substituted N-alkoxyimides and -amides as potential atypical antipsychotic agents

DOI: 10.1021/jm00107a028

Source and publish data:

Journal of Medicinal Chemistry p. 1068 - 1072 (1991)

Update date:2022-08-05

Topics:

Authors:

Hrib Hrib

Jurcak Jurcak

Huger Huger

Errico Errico

Dunn Dunn

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Article abstract of DOI:10.1021/jm00107a028

In a continuing program to discover antipsychotic agents with a reduced propensity toward extrapyramidal side-effects, a series of N-alkoxyimides and -amides was prepared. Evaluation of these compounds in vitro revealed affinities for D₂, 5HT View More

Full text of DOI:10.1021/jm00107a028

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