Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 13: Synthesis of fluorine-containing diaryltriazine derivatives for in vitro anti-HIV evaluation against wild-type strain

Article abstract of DOI:10.1002/cbdv.200800163

A series of diaryltriazine derivatives modified at C(2) of the triazine ring with a fluorinated phenyl group has been synthesized and tested for the ability to inhibit HIV-1 replication. Most of these F-containing compounds showed low-to-moderate anti-HIV