SYNTHESIS AND NITRATION OF SOME 4-CYCLOPROPYL- AND 4-(p-CYCLOPROPYLPHENYL)-2-AMINOTHIOPHENES

Article abstract of DOI:10.1007/BF00479336

A number of cyclopropyl-substituted crotononitriles have been synthesized by a Knoevenagel condensation. Reaction of these compounds with sulfur in the presence of a base gives substituted 4-cyclopropyl- and 4-cyclopropylphenyl-2-aminothiophenes, while nitration of some acetylaminothiophenes with acetyl nitrate in acetic anhydride at low temperature gives the corresponding nitro derivatives.