Tetrahedron p. 5095 - 5100 (1988)
Update date:2022-08-05
Topics:
Saalfrank, R. W.
Hafner, W.
Markmann, J.
Bestmann, H.-J.
Starting from enolizing 1,2-diketones 5 and (2,2-diethoxyvinylidene)triphenylphosphorane (2) or from 5 and (2,2-diethoxyvinyl)triphenylphosphonium tetrafluoroborate (6) the orthoesters 9 are prepared. 9 can be hydrolyzed under acidic conditions to give 5-alkylidene-2(5H)-furanones 10.Reaction of 1,2-hydroxyketones 11 and (2,2-ditehoxyvinylidene)triphenylphosphorane (2) via Michael addition and Wittig reaction yields orthoesters 15, which can be hydrolyzed to give 2(5H)-furanones 16 and 2-ethoxyfurans 17 respectively.A considerable variation of the substitens (R4)can be achieved starting from 11 and (2,2-diethoxyvinyl)triphenylphosphonium tetrafluoroborates 12.
View MoreWuhan Benjamin Pharmaceutical Chemical Co.,Ltd
Contact:86-27-52341789
Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Hangzhou Taiyan Trading Co., Ltd(expird)
Contact:+86-13777583958
Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
Chengdu Chengnuo New-Tech Co., Ltd
Contact:0086-028-85749078
Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Qingdao XinYongAn Chemicals Co., Ltd
Contact:+86-532-81107967
Address:Chengyang dual-port industrial park by the sea，Qingdao
Contact:86-28-61993785
Address:No.70-13-21, North Section, Erhuan
Doi:10.1039/b9nj00296k
(2010)Doi:10.1016/j.bmcl.2009.04.051
(2010)Doi:10.1021/je900609f
(2010)Doi:10.1016/j.tetasy.2009.09.024
(2009)Doi:10.1080/15257770903044184
(2009)Doi:10.1002/anie.200904603
(2009)
