Tetrahedron p. 5095 - 5100 (1988)
Update date:2022-08-05
Topics:
Saalfrank, R. W.
Hafner, W.
Markmann, J.
Bestmann, H.-J.
Starting from enolizing 1,2-diketones 5 and (2,2-diethoxyvinylidene)triphenylphosphorane (2) or from 5 and (2,2-diethoxyvinyl)triphenylphosphonium tetrafluoroborate (6) the orthoesters 9 are prepared. 9 can be hydrolyzed under acidic conditions to give 5-alkylidene-2(5H)-furanones 10.Reaction of 1,2-hydroxyketones 11 and (2,2-ditehoxyvinylidene)triphenylphosphorane (2) via Michael addition and Wittig reaction yields orthoesters 15, which can be hydrolyzed to give 2(5H)-furanones 16 and 2-ethoxyfurans 17 respectively.A considerable variation of the substitens (R4)can be achieved starting from 11 and (2,2-diethoxyvinyl)triphenylphosphonium tetrafluoroborates 12.
View MoreHenan Sinotech Import&Export Corporation
website:http://www.hasinotech.com
Contact:86-371-86181678
Address:No. 260, Dongming Road,Jinshui District
Luojiang Chenming Biological Products Co
Contact:+86 15000297032
Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Contact:86-513-84128750/13773795976
Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Contact:86-574-26865651
Address:529 YuanBaoShan Road, Beilun District
Contact:86-551-62628115
Address:No 36 Chuangye Road,Xuancheng Economic and Technological Development Zone,Anhui Province,P.R.China
Doi:10.1039/b9nj00296k
(2010)Doi:10.1016/j.bmcl.2009.04.051
(2010)Doi:10.1021/je900609f
(2010)Doi:10.1016/j.tetasy.2009.09.024
(2009)Doi:10.1080/15257770903044184
(2009)Doi:10.1002/anie.200904603
(2009)
