Novel synthetic isoquinolino[5,4-ab]phenazines: Inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities

DOI: 10.1016/j.bmc.2005.07.029

Source and publish data:

Bioorganic and Medicinal Chemistry p. 5909 - 5914 (2005)

Update date:2022-08-03

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Authors:

Yang, Peng

Yang, Qing

Qian, Xuhong

Cui, Jingnan

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Article abstract of DOI:10.1016/j.bmc.2005.07.029

The novel DNA interactive isoquinolino[5,4-ab]phenazine derivatives were designed and synthesized. Their inhibitory abilities toward topoisomerase I, antitumor activities and DNA photo-cleaving abilities were examined. The substituents at peri sites of tw

Full text of DOI:10.1016/j.bmc.2005.07.029

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