[3+2] Dipolar cycloadditions of an unstabilised azomethine ylide under continuous flow conditions

Article abstract of DOI:10.1016/j.tetlet.2009.12.071

The [3+2] dipolar cycloaddition reactions of the unstabilised azomethine ylide precursor benzyl(methoxymethyl)(trimethylsilylmethyl)amine with 12 electron-deficient alkenes in the presence of catalytic trifluoroacetic acid are examined under continuous fl