Journal of Organic Chemistry p. 5458 - 5461 (2008)
Update date:2022-09-26
Topics:
Verniest, Guido
Surmont, Riccardo
Van Hende, Eva
Deweweire, Arvid
Deroose, Frederik
Thuring, Jan Willem
De Kimpe, Norbert
(Chemical Equation Presented) Difluoropiperidines attract considerable interest from organic and medicinal chemists, but their synthesis is often problematic. This paper describes a new synthetic pathway toward valuable 3,3-difluoropiperidines starting fr
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