Synthesis and evaluation of some nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups as novel hypoxic cell selective cytotoxic agents

DOI: 10.1021/jm00114a024

Source and publish data:

Journal of Medicinal Chemistry p. 3132 - 3138 (1991)

Update date:2022-08-04

Topics:

Authors:

Saari Saari

Schwering

Lyle Lyle

Engelhardt

Sartorelli

Rockwell

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00114a024

Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl) benzenesulfonamide hy

Full text of DOI:10.1021/jm00114a024

Products guided by the article

Product name:4-chloro-N-[2-(dimethylamino)ethyl]-N-methyl-3-nitroBenzenesulfonamide

Cas No:126813-39-6

R&D Labs maybe for 126813-39-6

Anhui Xinyuan Technology Co.,Ltd

Contact:0086-559-3515800

Address:No.16 Zijin Rd, Circular Economic Zone, Huizhou District, Huangshan Anhui China
Yueyang Hudex Pharmaceuticals Ltd.

Contact:0730-8748800

Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone
Chengdu King-tiger Pharm-chem. Tech. Co., Ltd

Contact:028-85317716

Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.
Wuhan Hanye Chemical New Material Co.,Ltd

Contact:+86-27-85308141

Address:LiuDian, Panlongcheng Economic Development Zone, HuangPi district, Wuhan, Hubei 430311 P.R.China
Zhengzhou Gecko Scientific Inc.

Contact:0371-88884176

Address:56 Hongzhuan Road, Zhengzhou, China

Relevant to this article

Copper-catalyzed three-component coupling of terminal alkyne, dihalomethane and amine to propargylic amines

Doi:10.1002/adsc.201000691
(2011)
A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides e and F

Doi:10.1016/j.tet.2010.11.107
(2011)
Iodine- And TBHP-Promoted Acylation of Benzothiazoles under Metal-Free Conditions

Doi:10.1055/s-0040-1707204
(2020)
Mesomorphism and luminescence properties of platinum(II) complexes with tris(alkoxy)phenyl-functionalized pyridyl pyrazolate chelates

Doi:10.1002/chem.201000994
(2011)
Synthetic Study toward the Total Synthesis of Taxezopidines A and B

Doi:10.1021/acs.orglett.8b02571
(2018)
A highly efficient, large-scale, asymmetric direct aldol reaction employing simple threonine derivatives as recoverable organocatalysts in the presence of water

Doi:10.1002/ejoc.201001396
(2011)

Article Doi