Synthesis and evaluation of some nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups as novel hypoxic cell selective cytotoxic agents

DOI: 10.1021/jm00114a024

Source and publish data:

Journal of Medicinal Chemistry p. 3132 - 3138 (1991)

Update date:2022-08-04

Topics:

Authors:

Saari Saari

Schwering

Lyle Lyle

Engelhardt

Sartorelli

Rockwell

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Article abstract of DOI:10.1021/jm00114a024

Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl) benzenesulfonamide hy

Full text of DOI:10.1021/jm00114a024

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Product name:4-chloro-N-[2-(dimethylamino)ethyl]-N-methyl-3-nitroBenzenesulfonamide

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