86532-26-5Relevant articles and documents
Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F] fluoroanilino)quinazolines, potential EGFR imaging probes
Vasdev, Neil,Dorff, Peter N.,O'Neil, James P.,Chin, Frederick T.,Hanrahan, Stephen,Vanbrocklin, Henry F.
, p. 2959 - 2965 (2011)
Epidermal growth factor receptors (EGFR), upregulated in many tumor types, have been a target for therapeutic development and molecular imaging. The objective of this study was to evaluate the distribution and metabolic characteristics of fluorine-18 labe
A general protocol for Cu-mediated fluoro-deamination: Sandmeyer fluorination of diverse aromatic substrates
Pérez-García, R. Manuel,Gr?nnevik, Gaute,Riss, Patrick J.
supporting information, p. 1011 - 1015 (2021/02/16)
A Cu(I)-mediated fluoro-deamination method for nucleophilic radiofluorination was devised. The method affords fluorinated aromatic products directly from anilines under both no-carrier added and stoichiometric conditions. Isolated radiochemical yields ran
Synthesis of [18F]Fluoroarenes by Nucleophilic Radiofluorination of N-Arylsydnones
Narayanam, Maruthi Kumar,Ma, Gaoyuan,Champagne, Pier Alexandre,Houk, Kendall N.,Murphy, Jennifer M.
, p. 13006 - 13010 (2017/09/28)
A practical method for radiofluorination of anilines with [18F]fluoride via N-arylsydnone intermediates is described. These precursors are stable, easy to handle and facilitate direct and regioselective 18F-labeling to prepare [
