Preparation and utility of 5-β-D-ribofuranosyl-1H-tetrazole as a key synthon for C-nucleoside synthesis

Article abstract of DOI:10.1080/15257779408013218

A synthesis of 5-β-D-ribofuranosyl-1H-tetrazole (2) and 5-β-D- ribofuranosyl-l,3,4-oxadiazole-2(3H)-one (9) derivatives is described. Ring transformations of 2 have been investigated in an effort to establish the stability of this synthon for further use

Full text of DOI:10.1080/15257779408013218

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Preparation and Utility of 5-β-D-
Ribofuranosyl-1H-tetrazole as a Key
Synthon for C-Nucleoside Synthesis
J. Kobe a , M. Prhavc b , M. Hohnjec a & L. B. Townsend c
a National Institute of Chemistry , Hajdrihova 19, 61000, Ljubljana,
Slovenia
b Krka, Pharmaceutical and Chemical Works , 68000 Novo mesto,
Slovenia
c Department of Medicinal Chemistry and Department of Chemistry ,
College of Pharmacy, University of Michigan , Ann Arbor, Michigan,
48109, U.S.A.
Published online: 24 Sep 2006.
To cite this article: J. Kobe , M. Prhavc , M. Hohnjec & L. B. Townsend (1994) Preparation and Utility
of 5-β-D-Ribofuranosyl-1H-tetrazole as a Key Synthon for C-Nucleoside Synthesis, Nucleosides and
Nucleotides, 13:10, 2209-2244, DOI: 10.1080/15257779408013218
To link to this article: http://dx.doi.org/10.1080/15257779408013218
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