Journal of Medicinal Chemistry p. 887 - 900 (1991)
Update date:2022-08-05
Topics:
Williams, Peter D.
Perlow, Debra S.
Payne, Linda S.
Holloway, M. Katharine
Siegl, Peter K. S.
et al.
A series of renin inhibitors containing lactam-bridged P1-P1' dipeptide mimetics based on the ACHPA (4(S)-amino-5-cyclohexyl-3(S)-hydroxypentanoic acid) design was studied.The inhibitors were obtained by aldol addition of various lac
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