Renin Inhibitors Containing Conformationally Restricted P1-P1' Dipeptide Mimetics

DOI: 10.1021/jm00107a004

Source and publish data:

Journal of Medicinal Chemistry p. 887 - 900 (1991)

Update date:2022-08-05

Topics:

Authors:

Williams, Peter D.

Perlow, Debra S.

Payne, Linda S.

Holloway, M. Katharine

Siegl, Peter K. S.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00107a004

A series of renin inhibitors containing lactam-bridged P₁-P₁' dipeptide mimetics based on the ACHPA (4(S)-amino-5-cyclohexyl-3(S)-hydroxypentanoic acid) design was studied.The inhibitors were obtained by aldol addition of various lac

Full text of DOI:10.1021/jm00107a004

Products guided by the article

Product name:2(S)-<(tert-butyloxycarbonyl)amino>-3-cyclohexyl-1(S)-hydroxy-1-(1-butyl-5,5-dimethyl-2-oxopyrrolidin-3(S)-yl)propane

Cas No:129896-92-0

R&D Labs maybe for 129896-92-0

WUHAN RISON TRADING CO.,LTD

Contact:0086-27-83607103/83642615

Address:No.498, Jianshe Ave, Wuhan, China
KODI CHEMICAL CO., LTD

Contact:021

Address:Pudong
SuZhou LaiTeou

Contact:+86-0512-88957371

Address:shanghai
GUANGZHOU MEDCAN PHARMATECH LTD

website:http://www.gzmedcan.com

Contact:+86-20-82519649

Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China

Relevant to this article

Doi:10.1016/S0040-4020(01)83078-7
(1969)
Doi:10.1246/bcsj.46.2221
(1973)
Electron Capture Negative Ion and Positive Ion Chemical Ionization Mass Spectrometry of Polychlorinated Phenoxyanisoles.

Doi:10.1002/oms.1210200210
(1985)
Synthesis of unusual bicyclic nucleosides bearing an unsaturated side-chain, as potential inhibitors of varicella-zoster virus (VZV)

Doi:10.1081/NCN-120022661
(2003)
Investigation on the coordination mode of IL-supported diols used as phosphine-free ligands for palladium catalyzed heck reaction

Doi:10.1002/cjoc.201300461
(2013)
Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Specificity of the S-adenosylhomocysteine binding site.

Doi:10.1021/jm00263a008
(1973)

Article Doi