SYNTHESIS OF STATINE FROM (S)-MALIC ACID; STEREOCONTROL VIA RADICAL CYCLIZATION

DOI: 10.1016/S0040-4039(00)92639-X

Source and publish data:

Tetrahedron Letters p. 401 - 404 (1991)

Update date:2022-08-03

Topics:

Authors:

Koot, Wim-Jan

Ginkel, Roel van

Kranenburg, Mirko

Hiemstra, Henk

Louwrier, Saskia

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)92639-X

Highly stereoselective syntheses of enantiomerically pure γ-amino acids statine and 4-epi-statine from (S)-malic acid are described by using, respectively, an intramolecular α-acylamino radical reaction and an intermolecular N-acyliminium allylsilane coupling.

Full text of DOI:10.1016/S0040-4039(00)92639-X

Products guided by the article

Product name:Acetic acid (2S,3S)-1-benzyl-2-(2-methyl-allyl)-5-oxo-pyrrolidin-3-yl ester

Cas No:132917-67-0

R&D Labs maybe for 132917-67-0

Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang
Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Jinan Hongfangde Pharmatech Co.,Ltd

Contact:86-531-88870908

Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
Cartoon Ingredients Co., Ltd

website:http://www.cartoonchem.com/

Contact:+86-25-58074918

Address:Room 2109, RuiHua Business Center,315 South ZhongShan Road, Nanjing 210001, China

Relevant to this article

Cationic gold- and silver-catalyzed cycloisomerizations of propargylic ureas: A selective entry to oxazolidin-2-imines and imidazolidin-2-ones

Doi:10.1002/adsc.201200905
(2013)
Reactions of α-haloacroleins with azides: Highly regioselective synthesis of formyl triazoles

Doi:10.1039/c9gc01129c
(2019)
Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors

Doi:10.1021/jm201118h
(2012)
Synthesis, structural characterization, solution behavior, and in vitro antiproliferative properties of a series of gold complexes with 2-(2′-pyridyl)benzimidazole as ligand: Comparisons of gold(III) versus gold(I) and mononuclear versus binuclear derivatives

Doi:10.1021/ic202639t
(2012)
Synthesis of carbazoles by gold(I)-catalyzed carbocyclization of 2-(enynyl)indoles

Doi:10.1055/s-0030-1259537
(2011)
Doi:10.1002/pol.1948.120030108
(1948)

Article Doi