Synthesis and antiangiogenic activity of new silybin galloyl esters

DOI: 10.1021/jm201034h

Source and publish data:

Journal of Medicinal Chemistry p. 7397 - 7407 (2011)

Update date:2022-09-26

Topics:

Authors:

Ga?ák, Radek

Valentová, Kate?ina

Fuksová, Kate?ina

Marhol, Petr

Kuzma, Marek

Medina, Miguel ángel

Oborná, Ivana

Ulrichová, Jitka

K?en, Vladimír

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Article abstract of DOI:10.1021/jm201034h

The synthesis of various silybin monogalloyl esters was developed, and their antiangiogenic activities were evaluated in a variety of in vitro tests with human umbilical vein endothelial cells (HUVECs). A structure-activity relationship (SAR) study found

Full text of DOI:10.1021/jm201034h

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Product name:3-O-[(3',4',5'-tri-O-benzyl)galloyl]silybin

Cas No:1337536-84-1

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