Tetrahedron Letters p. 5423 - 5424 (1991)
Update date:2022-07-30
Topics:
Brunet
Singh Batra
Aguilar
Garcia Ruano
The addition of cyanide with KCN/ZnI2/TMSCN to β-hydroxyketones (R1-CHOH-CO-R2, R1 = i-Pr, R2 = Me, Et, i-Bu, i-Pr, t-Bu, R1 = Et, R2 = t-Bu and R1 = Bn, Ph, R2 = i-Bu) produced syn β-hydroxycyanohydrins in 95% d.e.
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