Highly diastereoselective addition of cyanide to β-hydroxyketones

DOI: 10.1016/S0040-4039(00)92403-1

Source and publish data:

Tetrahedron Letters p. 5423 - 5424 (1991)

Update date:2022-07-30

Topics:

Authors:

Brunet Brunet

Singh Batra

Aguilar Aguilar

Garcia Ruano

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)92403-1

The addition of cyanide with KCN/ZnI₂/TMSCN to β-hydroxyketones (R₁-CHOH-CO-R₂, R₁ = i-Pr, R₂ = Me, Et, i-Bu, i-Pr, t-Bu, R₁ = Et, R₂ = t-Bu and R₁ = Bn, Ph, R₂ = i-Bu) produced syn β-hydroxycyanohydrins in 95% d.e.

Full text of DOI:10.1016/S0040-4039(00)92403-1

Products guided by the article

Product name:(2S,4R)-2,4-Dihydroxy-2,5-dimethyl-hexanenitrile

Cas No:138101-91-4

R&D Labs maybe for 138101-91-4

HAINAN JINYING IMPORT AND EXPORT CO. LTD

Contact:+86-898-32875423

Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA
SEA BRGIHT INDUSTRY CO.,LIMITED

Contact:0086 755 8622 3990

Address:Rm 17B3,GuangCaiXinTianDi Bldg,GuiMiao Rd,NanShan District,Shenzhen,China
Nanjing Fayekong Chemcial Co.,Ltd(expird)

Contact:86-25-58813444

Address:Rm 1503, Unit 1, Building 5, Zijinnanyuan, Nanjing, Jiangsu, China
Wuhan Chemwish Technology Co., Ltd

website:http://www.chemwish.com/

Contact:+86-27-67849912

Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China
Tianjin Emulsion Science&Technology Development Co.,Ltd

Contact:13901380442

Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China

Relevant to this article

Aryl-β-C-glucosidation using glucal boronate: Application to the synthesis of tri-O-methylnorbergenin

Doi:10.1016/j.tet.2012.05.035
(2012)
Photodegradation of Natural Substances: Photooxygenation and Ozonolysis of 4-Methoxy-7-methyl-5H-furo<3,2-g><1>benzopyran-5-one (Visnagin)

Doi:10.1002/prac.19933350303
(1993)
Synthesis and self-association properties of flexible guanidiniocarbonylpyrrole-carboxylate zwitterions in DMSO: Intra- versus intermolecular ion pairing

Doi:10.1021/jo070641d
(2007)
Stereoselective synthesis of β-substituted β-amino sulfones and sulfonamides via addition of sulfonyl anions to chiral N-sulfinyl imines

Doi:10.1021/ol053132b
(2006)
Synthesis and characterization of liquid crystalline materials incorporating the novel 4-amino-1,2,4-triazole and isonicotinic acid hydrazide moiety

Doi:10.1080/15421400801915050
(2008)
Vitamin syntheses via carbene complexes. III. Stereospecific synthesis of alkenylcarbene chromium complexes

Doi:10.1515/znb-1983-1106
()

Article Doi