Highly diastereoselective addition of cyanide to β-hydroxyketones

DOI: 10.1016/S0040-4039(00)92403-1

Source and publish data:

Tetrahedron Letters p. 5423 - 5424 (1991)

Update date:2022-07-30

Topics:

Authors:

Brunet Brunet

Singh Batra

Aguilar Aguilar

Garcia Ruano

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)92403-1

The addition of cyanide with KCN/ZnI₂/TMSCN to β-hydroxyketones (R₁-CHOH-CO-R₂, R₁ = i-Pr, R₂ = Me, Et, i-Bu, i-Pr, t-Bu, R₁ = Et, R₂ = t-Bu and R₁ = Bn, Ph, R₂ = i-Bu) produced syn β-hydroxycyanohydrins in 95% d.e.

Full text of DOI:10.1016/S0040-4039(00)92403-1

Products guided by the article

Product name:(2S,4R)-2,4-Dihydroxy-2,5-dimethyl-hexanenitrile

Cas No:138101-91-4

R&D Labs maybe for 138101-91-4

Angelisun(Chongqing) Pharmaceutical Co., LTD.

Contact:+86-23-68030926-816

Address:D1-7 Tech & Entrepreneurs Park, Kecheng Road, Erlang Hi-Tech Areas, Chongqing, China
Fusilin chemical science & technology co., ltd.

Contact:532-80698166/86057573, +86-400-669-7885

Address:School of Material Science & Engineering, Shandong Uinversity of Science & Technology, Huangdao Zone, Qindao, Shandong
Xinjiang Fufeng Biotechnologies Co., Ltd.

Contact:+86-539-7287111

Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
Jiangxi Global Natural Spice Co., Ltd.

website:https://www.jxhqxl.com/

Contact:+86-796-8106598

Address:No.89, Wenshan Road,South Industrial Park, Jishui County,Jiangxi Province

Relevant to this article

Aryl-β-C-glucosidation using glucal boronate: Application to the synthesis of tri-O-methylnorbergenin

Doi:10.1016/j.tet.2012.05.035
(2012)
Photodegradation of Natural Substances: Photooxygenation and Ozonolysis of 4-Methoxy-7-methyl-5H-furo<3,2-g><1>benzopyran-5-one (Visnagin)

Doi:10.1002/prac.19933350303
(1993)
Synthesis and self-association properties of flexible guanidiniocarbonylpyrrole-carboxylate zwitterions in DMSO: Intra- versus intermolecular ion pairing

Doi:10.1021/jo070641d
(2007)
Stereoselective synthesis of β-substituted β-amino sulfones and sulfonamides via addition of sulfonyl anions to chiral N-sulfinyl imines

Doi:10.1021/ol053132b
(2006)
Synthesis and characterization of liquid crystalline materials incorporating the novel 4-amino-1,2,4-triazole and isonicotinic acid hydrazide moiety

Doi:10.1080/15421400801915050
(2008)
Vitamin syntheses via carbene complexes. III. Stereospecific synthesis of alkenylcarbene chromium complexes

Doi:10.1515/znb-1983-1106
()

Article Doi