Potential Non-Steroidal Estrogens and Antiestrogens, IV Organic Azides in Heterocyclic Synthesis, Part 13 : Synthesis of Aza- and Diazacoumestrols via Azido Derivatives

Article abstract of DOI:10.1007/BF00815924

4-Chloro-3-aryl-coumarins and quinolones 2 a-e undergo thermolytic ring closure by reaction with sodium azide in refluxing dimethyl formamide to yield indolo<3,2-c>coumarins and indolo<3,2-c>quinolin-6(5H)-ones 6a-e.In the case of the coumarin 2a the azid