Free-radical synthesis of 3-(2-cyanoethyl)- and 3-(2-methoxycarbonylethyl)-2,3-dideoxy-α-D-erythro-pentofuranoside and their application in the synthesis of potential antiviral nucleosides

DOI: 10.1002/ardp.2503241203

Source and publish data:

Archiv der Pharmazie p. 953 - 958 (1991)

Update date:2022-08-03

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Authors:

Lau Lau

Walczak Walczak

Pupek Pupek

Buch Buch

Nielsen Nielsen

Pedersen

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Article abstract of DOI:10.1002/ardp.2503241203

Free-radical reaction of different carbohydrate educts 2, 5, and 7 with acrylonitrile in the presence of tributyltin hydride and a radical initiator (AIBN) gave the methyl 3-(2-cyanoethyl)-2,3-dideoxypentofuranosides 3a and 6. Similar reaction of 2 with m

Full text of DOI:10.1002/ardp.2503241203

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