Isolation, structure and synthesis of new diarylbutane lignans from Phyllanthus niruri: Synthesis of 5'-desmethoxy niranthin and an antitumour extractive

Article abstract of DOI:10.1016/S0040-4020(01)81005-X

The structures of three new lignans (1-3) and a phenolic lignan (4) isolated from Phyllanthus niruri have been determined. The structures (1-3) were confirmed by their total synthesis and that of (4) was by its conversion to (3). The synthesis of (±) 5'-d