Synthesis of sialic acid through aldol condensation of glucose with oxalacetic acid

DOI: 10.1016/S0040-4039(00)74122-0

Source and publish data:

Tetrahedron Letters p. 325 - 328 (1992)

Update date:2022-09-26

Topics:

Authors:

Yamamoto

Teshima Teshima

Inami Inami

Shiba Shiba

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Article abstract of DOI:10.1016/S0040-4039(00)74122-0

N-Acetylneuraminic acid (sialic acid) 1 was synthesized through relatively short steps from D-glucose via a key intermediate 1,5-lactone derivative obtained from the pyranose isomer of the aldol condensation products of D-glucose with oxalacetic acid.

Full text of DOI:10.1016/S0040-4039(00)74122-0

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