
Tetrahedron Letters p. 2847 - 2850 (1992)
Update date:2022-07-29
Topics:
Paterson, Ian
Cumming, John G.
The C19-C32/C17-C30 segment (-)-5 of swinholide A/misakinolide A was prepared in 15 steps (6percent yield) from (+/-)-13.Key steps include the Sharpless epoxidation, 13 -> 14, the acetal allylation, 12 -> 16, the anti aldol, 17 + 11 -> 9, and the alkene h
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