Reaction of Dianions of Acyclic β-Enamino Ketones with Electrophiles. 3. Nitriles: Synthesis of Pyridine and Pyrimidine Derivatives

DOI: 10.1021/jo00048a043

Source and publish data:

Journal of Organic Chemistry p. 6020 - 6025 (1992)

Update date:2022-08-05

Topics:

Authors:

Bartoli, Giuseppe

Bosco, Marcella

Cimarelli, Cristina

Dalpozzo, Renato

De Munno, Giovanni

et al. et al.

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Article abstract of DOI:10.1021/jo00048a043

A new method for the construction of pyridine and pyrimidine derivatives is described, based on the electrophilic attack of nitriles to dianions of β-(monoalkylamino)-α,β-unsaturated ketones and the subsequent cyclization of the addition product.The react

Full text of DOI:10.1021/jo00048a043

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