NOVEL SYNTHESIS OF 4-BROMO-3-OXO-2-PHENYLHYDRAZONO-BUTYRONITRILE AND 4-CYANO-3-OXO-2-PHENYLHYDRAZONO-BUTYRONITRILE: SYNTHESIS OF PYRIDAZINE, THIAZOLE, 1,2,4-TRIAZINE AND PYRIDO-1,2,4-TRIAZINE DERIVATIVES

DOI: 10.1135/cccc19921758

Source and publish data:

Collection of Czechoslovak Chemical Communications p. 1758 - 1769 (1992)

Update date:2022-07-30

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Authors:

Mohareb, Rafat Milad

Abdel-Sayed, Nadia Iskander

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Article abstract of DOI:10.1135/cccc19921758

4-Bromo-3-oxo-2-phenylhydrazono-butyronitrile (II) reacted with thioamides to afford the thiazole derivatives III and IV.Compound II reacted with nucleophilic reagents to afford XIIIa and XIIIb.The reactivity of XIIIa with some chemical reagents was studied to afford pyridazine, thiazole, 1,2,4-triazine derivatives.

Full text of DOI:10.1135/cccc19921758

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