Asymmetric synthesis of camptothecin alkaloids: A nine-step synthesis of (S)-camptothecin

DOI: 10.1016/S0040-4039(00)73492-7

Source and publish data:

Tetrahedron Letters p. 5331 - 5334 (1994)

Update date:2022-08-04

Topics:

Authors:

Comins, Daniel L.

Hong, Hao

Jianhua, Gao

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73492-7

DE Ring camptothecin intermediate II was prepared enantioselectively from 2-chloro-6 hydroxypyridine in six steps and used in a nine-step synthesis of (S)-camptothecin.

Full text of DOI:10.1016/S0040-4039(00)73492-7

Products guided by the article

Product name:4(S)-4-ethyl-4-hydroxy-6-chloro-4,7-dihydro-1H-pyrano[3,4-c]pyridin-3,8-dione

Cas No:146683-26-3

R&D Labs maybe for 146683-26-3

Shanghai Apeptide Co., Ltd.

website:http://www.apeptides.com/en/

Contact:+86-21-60871011

Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai
Hebei Maison Chemical Co.,Ltd

website:http://www.maisonchem.com.cn

Contact:0086-311-83833777

Address:Leitou industrial district, xinji, shijiazhuang city, hebei province,
Xi'an Unique Electronic and Chemical Co., Ltd.

Contact:+86-029-88238008

Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Jiangsu Institute of Ecomones Co., Ltd

website:http://www.jsmone.com

Contact:+86-519-82821700

Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road

Relevant to this article

REACTIVITY OF 2-t-BUTYL-4,5-DIDEHYDROPYRIMIDINE AND ELECTRONIC STRUCTURE OF THE PARENT HETARYNE

Doi:10.1016/S0040-4020(01)88355-1
(1992)
The development of hydrazide γ-Turn mimetics

Doi:10.1016/S0040-4039(97)01664-X
(1997)
Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: Synthesis and biological activity

Doi:10.1016/j.ejmech.2013.07.014
(2013)
Gentiobiosylation of β-resorcylic acid esters and lactones: First synthesis and characterization of zearalenone-14-β,d-gentiobioside

Doi:10.1055/s-0033-1339338
(2013)
2-(N,N-diethylcarbamoyloxy) allylsilane. Dual reactivity with α,α′-acetone dianion and allene 1,2-dipole equivalency

Doi:10.1016/0040-4039(93)85089-F
(1993)
Ex Situ Enantioconvergent Approaches for the Effective Use of Undesired Isomers: Stereochemical Convergence of a Substrate with Multiple Chiral Centers and Recycling of a Decarboxylated Byproduct

Doi:10.1055/s-0035-1561620
(2016)

Article Doi