Selective Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. New 2,3-Dihydrothiazoloisoindol-5(9bH)-ones and Related Compounds with Anti-HIV-1 Activity

DOI: 10.1021/jm00069a011

Source and publish data:

Journal of Medicinal Chemistry p. 2526 - 2535 (1993)

Update date:2022-07-30

Topics:

Authors:

Mertens, Alfred

Zilch, Harald

Koenig, Bernhard

Schaefer, Wolfgang

Poll, Thomas

et al. et al.

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Article abstract of DOI:10.1021/jm00069a011

A series of substituted 2,3-dihydrothiazolo<2,3-a>isoindol-5(9bH)-ones and related compounds 1-73 were synthesized and evaluated for their ability to inhibit reverse transcriptase (RT) of the human immune deficiency virus 1 (HIV-1) and replication of HIV-

Full text of DOI:10.1021/jm00069a011

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