Regioselective synthesis of 1,3,5-Trisubstituted Pyrazoles from N-Alkylated Tosylhydrazones and terminal Alkynes

DOI: 10.1021/ol403447g

Source and publish data:

Organic Letters p. 576 - 579 (2014)

Update date:2022-07-30

Topics:

Authors:

Kong, Yuanfang

Tang, Meng

Wang, Yun

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Article abstract of DOI:10.1021/ol403447g

An efficient synthesis of 1,3,5-trisubstituted pyrazoles from Nalkylated tosylhydrazones and terminal alkynes was developed. The protocol was applied to a wide range of substrates and demonstrated excellent tolerance to a variety of substituents, includin

Full text of DOI:10.1021/ol403447g

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