Synthesis and biological evaluation of novel cyclic enediyne compounds related to dynemicin A as antitumor agents

DOI: 10.1248/cpb.45.125

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 125 - 133 (1997)

Update date:2022-08-05

Topics:

Authors:

Unno, Ryoichi

Michishita, Hisashi

Inagaki, Hideaki

Baba, Yutaka

Jomori, Takahito

Nishikawa, Toshio

Isobe, Minoru

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.125

Novel cyclic enediyne compounds, which are simple functional analogs of dynemicin A (1) having the bicyclo[7.3.1]tridec-4-ene-2,6-diyne system, were synthesized and evaluated for the DNA-cleaving ability, in vitro cytotoxicity and in vivo antitumor activi

Full text of DOI:10.1248/cpb.45.125

NII-Electronic Library Service

Products guided by the article

Product name:4-[1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-ethynyl-2H-quinoline-1-carboxylic acid phenyl ester

Cas No:163392-55-0

R&D Labs maybe for 163392-55-0

Qingdao Xinnuo pharmaceutical Chemical Co.,Ltd

Contact:86-186-15688656

Address:50 Meters North To YuanHou Community Committee,Xifuzhen Subdistrict,Chengyang District,Qingdao
Shanghai PuYi Chem-Tech Co.,Ltd.

Contact:+86-21-57687505-227

Address:3 Floor, Building 11, No 201 MinYi Road, Songjiang District, Shanghai 201612, China
MedicalChem(Yancheng)Manuf.Co.,Ltd.

Contact:+86-515-84383366

Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD

Contact:+86-571-88932183

Address:Hangzhou
WUHAN BIOCATA BIOLOGICAL TECHNOLOGY CO,.LTD

Contact:86-13812081281

Address:wuhan donghu

Relevant to this article

Break-and-Build Strategy for the Synthesis of 2-Benzoylbenzoxazoles from o-Aminophenols and Acetophenones

Doi:10.1002/adsc.202100150
(2021)
Di(phenoxo)-bridged Dinuclear Mn2(II,II) and Mn2(II,III) Complexes of Macrocyclic Ligands: Structure, Properties, and Catalase-Like Function

Doi:10.1246/bcsj.68.1105
(1995)
In vitro antioxidant and cytotoxic activity of some synthetic riparin-derived compounds

Doi:10.3390/molecules19044595
(2014)
Antibacterial activity of glycine betaine analogues: Involvement of osmoporters

Doi:10.1016/j.bmcl.2004.02.045
(2004)
The reaction of 1-phenylpyrazolidine-3,5-dione with active nitriles using phase transfer catalysis conditions technique

Doi:10.1002/jhet.1786
(2014)
Doi:10.1039/jr9490001028
(1949)

Article Doi