
Chemical and Pharmaceutical Bulletin p. 125 - 133 (1997)
Update date:2022-08-05
Topics:
Unno, Ryoichi
Michishita, Hisashi
Inagaki, Hideaki
Baba, Yutaka
Jomori, Takahito
Nishikawa, Toshio
Isobe, Minoru
Novel cyclic enediyne compounds, which are simple functional analogs of dynemicin A (1) having the bicyclo[7.3.1]tridec-4-ene-2,6-diyne system, were synthesized and evaluated for the DNA-cleaving ability, in vitro cytotoxicity and in vivo antitumor activi
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(1949)