Bioorganic and Medicinal Chemistry Letters p. 81 - 86 (1998)
Update date:2022-08-02
Topics:
Tanaka, Akira
Terasawa, Takeshi
Hagihara, Hiroyuki
Kinoshita, Takayoshi
Sakuma, Yuri
Ishibe, Noriko
Sawada, Masae
Takasugi, Hisashi
Tanaka, Hirokazu
The synthesis, single crystal X-ray structural analysis, and biological activity of FR186054 (2c), a new, potent, orally efficacious inhibitor of acyl-CoA: cholesterol O-acyltransferase (ACAT), containing a pyrazole ring are described. This compound displ
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