SYNTHESIS OF 3-HYDROXYSPERMIDINE: AN UNUSUAL POLYAMINE CONSTITUENT OF CYTOTOXIC MARINE COMPOUNDS

DOI: 10.1016/0040-4039(95)01976-O

Source and publish data:

Tetrahedron Letters p. 9109 - 9112 (1995)

Update date:2022-07-30

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Authors:

Ponasik, James A.

Ganem, Bruce

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Article abstract of DOI:10.1016/0040-4039(95)01976-O

A short, convergent synthesis of the title compound, (+/-)-N¹-(3-aminopropyl)-1,4-diamino-2-butanol 6, was accomplished in 42percent overall yield by means of a highly regioselective 1,3-dipolar nitrone cycloaddition.

Full text of DOI:10.1016/0040-4039(95)01976-O

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