Tetrahedron Letters p. 5583 - 5586 (1997)
Update date:2022-07-30
Topics:
Semmelhack
Gu, Yansong
Ho, Douglas M.
An enediyne unit in a bicyclo[8.3.0] framework with a trans ring fusion has been designed, synthesized, and evaluated as a new functional model for the enediyne toxins. The cycloaromatization reaction proceeds with a half-life time of 13-14 hr at 25°C.
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Doi:10.1016/S0040-4020(97)00837-5
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