Bioorganic and Medicinal Chemistry Letters p. 47 - 50 (1998)
Update date:2022-09-26
Topics:
Neel, David A.
Jirousek, Michael R.
McDonald III, John H.
Bisindolylmaleimides are known to be potent and selective PKC inhibitors. A new synthesis of this class of compound is reported. The key step is a Suzuki cross-coupling reaction using a readily available indolylmaleimide triflate intermediate.
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