
Advanced Synthesis and Catalysis p. 264 - 268 (1998)
Update date:2022-08-03
Topics:
Meisel, Roland
Peseke, Klaus
Reinke, Helmut
2,3,4,5,6-Penta-O-acetyl-D-galactonic acid chloride (1a) and D-gluconic acid chloride (1b), respectively, react with alkyl acetoacetates and benzoylacetates 2, respectively, to yield derivatives 3 of diuloses with an alkoxycarbonyl group in the branch. Decarboalkoxylation of these compounds gives 1,3-didesoxy-nono-2,4-diuloses 4a,b and 2-deoxy-octo-1,3-diuloses 4c, respectively. Compound 4a and diazomethane react to furnish the corresponding methyl enol ether 5a and 5b.
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