Cyano and Nitro Group Effect on the Rate of Methoxy Denitration Reaction in the Pyrrole and Benzene Ring

Article abstract of DOI:10.1021/jo00187a014

In both the pyrrole and benzene ring the methoxy denitration reaction is accelerated by a nitro or a cyano group flanking the reaction center.However, because of the different geometry of the rings, in the pyrrole ring a nitro group is more effective than a cyano group, at variance whit what is observed in the benzene ring.