Synlett p. 1613 - 1618 (2020)
Update date:2022-09-26
Topics:
Liu, Yuxia
Wang, Chao
Huang, Linjuan
Xue, Dong
A palladium(II)-catalyzed direct 2-arylation of indoles by tetraarylstannanes with oxygen (balloon) as the oxidant at room temperature has been developed. Various tetraarylstannanes can be employed as aryl sources for 2-arylation of indoles in up to 89% yield, providing a practical and efficient catalytic protocol for accessing 2-arylindoles.
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