Ones, thiones, and N-oxides: An eercise in imidazole chemistry

DOI: 10.1002/1521-3773(20020703)41:13<2290::AID-ANIE2290>3.0.CO;2-R

Source and publish data:

Angewandte Chemie - International Edition p. 2290 - 2293 (2002)

Update date:2022-07-29

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Authors:

Laufer, Stefan

Wagner, Gerd

Kotschenreuther, Dunja

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Article abstract of DOI:10.1002/1521-3773(20020703)41:13<2290::AID-ANIE2290>3.0.CO;2-R

Regioselective synthetic approaches to tetrasubstituted imidazoles (see picture) are reported. These highly substituted heterocycles are potent inhibitors of cytokine release and therefore interesting candidates for anti-inflammatory drugs.

Full text of DOI:10.1002/1521-3773(20020703)41:13<2290::AID-ANIE2290>3.0.CO;2-R

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