Synthesis and taste properties of 4,1′,4′,6′-tetrahalodeoxysncrose analogues

Article abstract of DOI:10.1081/CAR-120021700

The synthesis of a series of 1,4,6-trideoxy-1,4,6-trihalo-β-D-hexulofuranosyl 4-deoxy-4-halo-α-D-hexopyranosides is described. The 4-chloro-, 4-bromo- and 4-iodo-4-deoxy-β-D-fructofuranosyl analogues were synthesized from a 3′,4′-lyxo-epoxide using the re