Solvent Effects on the Basicity of Alkyl-Substituted Dimethylamines

Article abstract of DOI:10.1021/jo00237a017

The basicity of alkyl-substituted dimethylamines in various solvents is dictated largely by specific solvation of the ammonium ion.Solvent attenuation factors, which reflect the extent to which solvents solvate ions, are directly proportional to the solvent's hydrogen bond acceptor ability, β.Substituent polarizability attenuation factors indicate that charge-induced stabilization varies in different solvents.