LiAlH4-Promoted Tandem Reduction/Oxidation of Fluorenyl Derivatives under Air

Article abstract of DOI:10.1002/ejoc.201402642

The tandem reduction/oxidation of fluorenyl compounds was performed with LiAlH₄ under air to afford the corresponding 9-hydroxyfluorenyl derivatives in good yields. This methodology with LiAlH₄ is unprecedented and most likely proceeds by an organoaluminium intermediate, and in the proposed mechanism. The tandem reduction/oxidation of fluorenyl compounds with LiAlH₄ under air affords the corresponding 9-hydroxyfluorenyl derivatives in good yields.