Chemistry of Heterocyclic Compounds p. 1051 - 1053 (1980)
Update date:2022-07-29
Topics:
Kucherova, N. F.
Sipilina, N. M.
Novikova, N. N.
Silenko, I. D.
Rozenberg, S. G.
Zagorevskii, V. A.
A preparative method for the synthesis of 9-(2,2,2-trifluoroethyl)-1,2,3,4,4a,9a-hexahydro-γ-carbolines by the action of alkali metal borohydrides in trifluoroacetic acid on 1,2,3,4-tetrahydro-γ-carbolines was developed.The indicated trifluoroethyl derivatives can also be obtained by reaction of the same reagents with 1,2,3,4,4a,9a-hexahydro-γ-carbolines, which are intermediates in the overall reduction-trifluoroethylation process.
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(1978)
