Radical and palladium-catalyzed cyclizations to cyclobutenes: An entry to the BCD ring system of penitrem D

Article abstract of DOI:10.1021/jo049873s

A novel approach toward the synthesis of the BCD ring system of penitrem D is described. The strategy capitalizes on the fast cyclization rates of aryl radicals into cyclobutenes and allows access to a variety of fused tricyclic structures. Radical/polar