
Journal of Medicinal Chemistry p. 614 - 617 (1981)
Update date:2022-08-02
Topics:
Nelson, Wendel L.
Sneed, Cherilyn K.
Giacomini, Kathleen M.
Giacomini, John C.
Stauss, John
et al.
The 2R and 2S enantiomers of 4-isopropyl-2-(2-pyridyl)-2-phenylbutyramide <(2R)-2 and (2S)-2> were prepared from the respective 2R and 2S enantiomers of disopyramide <(2R)-1 and (2S)1> by oxidation with peracid, Cope elimination, and subsequent zinc/HCl r
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