Synthesis of new tridentate chiral aminoalcohols by a multicomponent reaction and their evaluation as ligands for catalytic asymmetric Strecker reaction

DOI: 10.1016/j.tet.2007.06.047

Source and publish data:

Tetrahedron p. 8727 - 8734 (2007)

Update date:2022-08-03

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Authors:

Banphavichit, Vorawit

Bhanthumnavin, Worawan

Vilaivan, Tirayut

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Article abstract of DOI:10.1016/j.tet.2007.06.047

A one-step, multicomponent Mannich-type reaction between phenols, paraformaldehyde, and β-aminoalcohols in the presence of LiCl afforded N-2-hydroxybenzyloxazolidines with high ortho-selectivity. Hydrolytic or reductive ring opening of the oxazolidines pr

Full text of DOI:10.1016/j.tet.2007.06.047

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