REACTION OF LITHIUM DIMETHYLCUPRATE WITH CONFORMATIONALLY BIASED β-ACYLOXY ENOL ESTERS - REGIO AND STEREOCONTROLLED ACCESS TO FUNCTIONALIZED SIX-CARBON CHIRAL SYNTHONS

Article abstract of DOI:10.1016/S0040-4039(01)82987-7

Alkyl 2-acyloxy α-D-erythro-hex-2-enopyranoside diesters, readily available from D-hexoses, are versatile intermediates for the expeditious preparation of six-carbon chiral synthons containing alternating and/or consecutive C-methyl and hydroxyl groups.