
Tetrahedron p. 1061 - 1068 (1983)
Update date:2022-08-05
Topics:
Adlington, Robert M.
Aplin, Robin T.
Baldwin, Jack E.
Chakravarti, Bulbul
Field, Leslie D.
et. al.
δ-(L-α-Amino<1,1,6-17O/18O>-adipyl)-L-cystinyl-D-valine was converted into isopenicillin N in cell-free extracts of Cephalosporium acremonium with no loss of 17O/18O label as shown by 17O NMR spectroscopy and mass spectrometry.Incubation of unlabelled tripeptide in a cell-free system containing 17O/18O enriched water produced isopenicillin N with no incorporation of 17O/18O.
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(1983)Doi:10.1016/j.bmc.2005.04.063
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(1981)